CBD, short for Cannabidiol, is a natural compound that is one of the two primary constituents found in Cannabis. Tetrahydrocannabidiol(THC) is the more stigmatized and frequently associated component of cannabis, has mind-altering effects which produce the well known marijuana “high.” CBD, is a safe, non-addictive and non-psychoactive component of Cannabis that has bountiful health benefits.

cbd molecular structure

CBD is one of more than a hundred “phytocannabinoids” which are unique to cannabis and endow the plant with its robust therapeutic profile. Phytocannabanoids work similarly to endocannabanoids, contained within our own body and are considered neurochemicals that are found throughout the nervous system and are connected to our immune response and even our reproductive system.
While both predominating cannabanoids have bountiful therapeutic effects, they communicate in very different ways with different receptors in the body and brain.

The Endocannabanoid System

CBD works with the Endocannabanoid System(ECS) in our body which serves as a regulatory infrastructure. The Endocannabinoid System is a network of cells throughout our body that have CBD receptors. The ECS is responsible for maintaining and restoring balance in our bodies. It’s aim is to cultivate homeostasis which is a stable internal environment. The ECS monitors and regulates the body’s constant struggle between building itself up(anabolism) and breaking itself down (catabolism)

cbd impact on endocannabanoid system in body

The ECS is comprised of two receptors:

  • Cannabinoid-1(CB1)
  • Cannabinoid-2(CB2)

And two signalign molecules

  • Arachidonyl athanolamide (AEA)
  • 2-Arachidonyl Glycerol 2-AG